- Cdc6 Mutants
- cdc6∆2-49
- cdh1∆ cdc6∆2-49
- sic1∆ cdc6∆2-49
- sic1∆ cdc6∆2-49 cdh1∆
- sic1∆ cdc6∆2-49 cdh1∆ GALL-CDC20
- swi5∆
- swi5∆ cdh1∆
- swi5∆ cdh1∆ GAL-SIC1
- swi5∆ GAL-CLB2
- CLB2-db∆ GAL-CDC6
- CLB2-db∆ multicopy CDC6
- APC-A cdh1∆ GAL-CDC6
- APC-A cdh1∆ multicopy CDC6
- APC-A sic1∆ cdc6∆2-49
swi5∆ GAL-CLB2
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksswi'=ksswi"=0, ksb2=0.12, MDT=150.
Arrest: Telophase arrest.
Experiments:
Toyn, J.H., Johnson, A.L., Donovan, J.D., Toone, W.M., Johnston, L.H. (1997). The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase. Genetics 145:85-96.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Inviable.
Comments: